Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.75 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 9/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | BCR | P11274 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493474 | 1.00 | TRPA1 (0.75) | TRPA1TRPM8RELANFE2L2ESR1 | |
| SCHEMBL4402914 | 0.98 | TRPA1 (0.71) | TRPA1TRPM8RELANFE2L2ESR1 | |
| SCHEMBL7873582 | 0.98 | TRPA1 (0.71) | TRPA1TRPM8RELANFE2L2ESR1 | |
| SCHEMBL8943877 | 0.98 | TRPA1 (0.71) | TRPA1TRPM8RELANFE2L2ESR1 | |
| SCHEMBL6819748 | 0.98 | TRPA1 (0.71) | TRPA1TRPM8RELANFE2L2ESR1 | |
| SCHEMBL5487752 | 0.98 | TRPA1 (0.78) | TRPA1TRPM8RELANFE2L2ESR1 | |
| SCHEMBL5487747 | 0.98 | TRPA1 (0.78) | TRPA1TRPM8RELANFE2L2ESR1 | |
| SCHEMBL8943882 | 0.98 | TRPA1 (0.71) | TRPA1TRPM8RELANFE2L2ESR1 | |
| SCHEMBL16492030 | 0.98 | TRPA1 (0.71) | TRPA1TRPM8RELANFE2L2ESR1 | |
| SCHEMBL7821780 | 0.98 | TRPA1 (0.71) | TRPA1TRPM8RELANFE2L2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7510809-B2 | Electrophotographic photoreceptor with two layer charge transfer layer, and apparatus utilizing the same | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-03-31 | — | — | US | disclosed |
| US-7276627-B2 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20060224017-A1 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2006-10-05 | — | — | US | disclosed |
| EP-0780363-B1 | Bisazo-benzofuran compounds, their use as charge carrier generating compounds | SHARP KK (JP) | 2001-09-26 | — | — | EP | disclosed |
| US-6022655-A | CHARGE TRANSFER COMPOUND | SHARP KABUSHIKI KAISHA (JP) | 2000-02-08 | — | — | US | disclosed |
| US-5853930-A | Electrophotographic photoconductors using bisazo compounds | SHARP KABUSHIKI KAISHA (JP) | 1998-12-29 | — | — | US | disclosed |
| EP-0780363-A1 | Bisazo-benzofuran compounds, their use as charge carrier generating compounds and intermediates for their preparation | SHARP KABUSHIKI KAISHA (JP) | 1997-06-25 | — | — | EP | disclosed |
| US-5501930-A | Electrophotographic photoreceptor containing enamine derivative | SHARP KABUSHIKI KAISHA (JP) | 1996-03-26 | — | — | US | disclosed |
| EP-0318916-B1 | Electrophotographic sensitive material | MITA INDUSTRIAL CO LTD (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-5389479-A | Excellent sensitivity in positive charge; multilayer consists of charge generating and charge transferring layer | SHARP KABUSHIKI KAISHA (JP) | 1995-02-14 | — | — | US | disclosed |
| US-4925759-A | Electrophotographic sensitive material with pyrrolopyrrole and benzidine derivatives | MITA INDUSTRIAL CO., LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0153145-B1 | PHOTORECEPTOR | KONICA CORPORATION (JP) | 1988-06-08 | — | — | EP | disclosed |
| EP-0156481-B1 | PHOTORECEPTOR | KONICA CORPORATION (JP) | 1988-06-08 | — | — | EP | disclosed |
| US-4579800-A | HIGH STABILITY WITH RESPECT TO LIGHT AND HEAT | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-04-01 | — | — | US | disclosed |
| US-4576886-A | ELECTROGRAPHY | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| EP-0156481-A2 | Photoreceptor | KONICA CORPORATION (JP) | 1985-10-02 | — | — | EP | disclosed |
| EP-0153145-A2 | Photoreceptor | KONICA CORPORATION (JP) | 1985-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060224017-A1 | One pot sequential reactions and novel products produced thereby | PNMT, CYP1A1, TERT | TRPA1 1677/4885TRPM8 2842/4885RELA 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.