Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 7/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944070 | 0.97 | GABRA1 (0.36) | CNR2GABRA1GABRB2CNR1FPR2 | |
| SCHEMBL8944337 | 0.96 | GABRA1 (0.35) | CNR2GABRA1GABRB2CNR1FPR2 | |
| SCHEMBL8944080 | 0.96 | GABRA1 (0.35) | CNR2GABRA1GABRB2CNR1FPR2 | |
| SCHEMBL8944441 | 0.96 | GABRA1 (0.35) | CNR2GABRA1GABRB2CNR1FPR2 | |
| SCHEMBL8944431 | 0.96 | GABRA1 (0.35) | CNR2GABRA1GABRB2CNR1FPR2 | |
| SCHEMBL8944426 | 0.95 | GABRA1 (0.39) | CNR2GABRA1GABRB2FPR2PDE4A | |
| SCHEMBL18718722 | 0.94 | CNR2 (0.34) | CNR2GABRA1GABRB2CNR1FPR2 | |
| SCHEMBL13579245 | 0.93 | CNR2 (0.37) | CNR2GABRA1GABRB2CNR1FPR2 | |
| SCHEMBL8944435 | 0.93 | KDM1A (0.36) | GABRA1GABRB2FPR2 | |
| SCHEMBL8944487 | 0.90 | FPR2 (0.33) | CNR2FPR2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |