SCHEMBL8944129

SCHEMBL8944129

CCCCOC(=O)CC(OCCCCl)OCCCCl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.42
ALDH1A1 P00352 2/20 0.41
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
MAPK1 P28482 2/20 0.38
MAPT P10636 1/20 0.38
DGKA P23743 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 3/20 0.37
HPGD P15428 1/20 0.37
RAD52 P43351 1/20 0.37
FAAH O00519 1/20 0.36
LMNA P02545 1/20 0.36
ESR1 P03372 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
NR1H2 P55055 1/20 0.36
RNASEL Q05823 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1879488 0.91 NAAA (0.48) NAAAALDH1A1ATML3MBTL1NPSR1
SCHEMBL1879519 0.88 NAAA (0.44) NAAAALDH1A1ATML3MBTL1NPSR1
SCHEMBL1884754 0.82 NAAA (0.47) NAAAALDH1A1ATML3MBTL1NPSR1
SCHEMBL1879615 0.82 ALDH1A1 (0.42) NAAAALDH1A1ATML3MBTL1NPSR1
SCHEMBL1883903 0.78 MAPT (0.41) NAAAALDH1A1ATMMAPTDGKA
SCHEMBL11090336 0.78 NAAA (0.39) NAAAALDH1A1L3MBTL1NPSR1MAPK1
SCHEMBL1879588 0.77 NAAA (0.48) NAAAALDH1A1ATML3MBTL1NPSR1
SCHEMBL1883376 0.77 CA12 (0.41) NAAAALDH1A1ATMDGKATSHR
SCHEMBL11571805 0.75 NAAA (0.47) NAAAALDH1A1ATML3MBTL1NPSR1
SCHEMBL29077537 0.75 NAAA (0.47) NAAAALDH1A1ATML3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639175-B1 PROCESS FOR PRODUCING 2-(DIALKYLOXY METHYL)-CARBOXYLIC ACID ESTERS HOECHST AG (DE) 1996-05-29 EP disclosed
US-5510512-A OXIDIZING ACETALIZATION OF ACRYLIC ACID ESTERS WITH ALCOHOLS IN PRESENCE OF OXYGEN AS OXIDANT AND CATALYST SYSTEM CONTAINING PLATINUM GROUP METAL OR COMPOUND AND COPPER COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed