SCHEMBL8944162

SCHEMBL8944162

CCCN(Cc1ccc(-c2ccccc2C(=N)NO)cc1)c1nn(C)cc1C(=O)OCC

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 20/20 0.54
AGTR2 P50052 19/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6610015 0.90 AGTR1 (0.53) AGTR1AGTR2
SCHEMBL8548779 0.87 LTB4R2 (0.48) AGTR1AGTR2
SCHEMBL8944455 0.84 AGTR1 (0.43) AGTR1AGTR2
SCHEMBL8944453 0.84 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL6609059 0.84 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL6606838 0.82 AGTR1 (0.53) AGTR1AGTR2
SCHEMBL6607280 0.82 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL9295593 0.80 AGTR1 (0.59) AGTR1AGTR2
SCHEMBL6608757 0.79 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL6605207 0.78 AGTR1 (0.53) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5500427-A ANGIOTENSIN II ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-03-19 US disclosed