Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 18/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 18/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609059 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL8944162 | 0.84 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL6608915 | 0.83 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL6607280 | 0.81 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL8944455 | 0.80 | AGTR1 (0.43) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL6604855 | 0.79 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL6608525 | 0.79 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8944447 | 0.79 | AGTR1 (0.36) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL6608757 | 0.78 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9542915 | 0.77 | AGT (0.46) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500427-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-19 | — | — | US | disclosed |