SCHEMBL8944174

SCHEMBL8944174

CCCCCOc1ccc(N(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.55
LTA4H P09960 5/20 0.53
AHR P35869 1/20 0.50
TP53 P04637 2/20 0.49
TSHR P16473 1/20 0.49
MAPT P10636 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
PLA2G4B P0C869 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
HPGD P15428 1/20 0.46
ATM Q13315 1/20 0.46
PTGES O14684 1/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
ALOX15 P16050 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944067 0.98 NR5A1 (0.58) NR5A1LTA4HAHRTP53TSHR
SCHEMBL8943974 0.98 NR5A1 (0.58) NR5A1LTA4HAHRTP53TSHR
SCHEMBL8943847 0.98 NR5A1 (0.58) NR5A1LTA4HAHRTP53TSHR
SCHEMBL8943679 0.98 NR5A1 (0.58) NR5A1LTA4HAHRTP53TSHR
SCHEMBL8943945 0.98 NR5A1 (0.58) NR5A1LTA4HAHRTP53TSHR
SCHEMBL8944313 0.96 AHR (0.53) NR5A1LTA4HAHRTSHRMAPT
SCHEMBL8943807 0.96 AHR (0.53) NR5A1LTA4HAHRTSHRMAPT
SCHEMBL8943684 0.92 LTA4H (0.58) NR5A1LTA4HTP53TSHRMAPT
SCHEMBL8943762 0.90 MAPT (0.54) AHRTSHRMAPTL3MBTL1TDP1
1-Methoxy-4-Pentoxybenzene SCHEMBL7778996 0.90 NR5A1 (0.64) NR5A1LTA4HAHRTP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed