SCHEMBL8943762

SCHEMBL8943762

COc1ccc(N(c2ccc(OC)cc2)c2ccc(OCCCOc3ccc(N(c4ccc(OC)cc4)c4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
HPGD P15428 1/20 0.54
ATM Q13315 1/20 0.54
DRD2 P14416 1/20 0.49
DRD4 P21917 1/20 0.49
DRD3 P35462 1/20 0.49
KCNH2 Q12809 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
RECQL P46063 1/20 0.46
MCHR1 Q99705 1/20 0.46
ALDH1A1 P00352 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
HSD17B10 Q99714 1/20 0.46
AHR P35869 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943807 0.94 AHR (0.53) MAPTL3MBTL1HPGDATMDRD2
SCHEMBL8944313 0.94 AHR (0.53) MAPTL3MBTL1HPGDATMDRD2
SCHEMBL8943774 0.93 L3MBTL1 (0.57) MAPTL3MBTL1HPGDATMDRD2
SCHEMBL8943677 0.93 ACHE (0.54) MAPTL3MBTL1HPGDATMDRD2
SCHEMBL8944174 0.90 NR5A1 (0.55) MAPTL3MBTL1HPGDATMTDP1
SCHEMBL8944354 0.90 TSHR (0.49) MAPTL3MBTL1HPGDATMMCHR1
SCHEMBL24495433 0.89 MCHR1 (0.45) MAPTL3MBTL1HPGDATMDRD2
SCHEMBL8943945 0.89 NR5A1 (0.58) MAPTL3MBTL1TDP1NPC1RAB9A
SCHEMBL8943912 0.89 DRD2 (0.56) MAPTL3MBTL1HPGDATMDRD2
SCHEMBL8943679 0.89 NR5A1 (0.58) MAPTL3MBTL1TDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed