Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944206 | 1.00 | TDP1 (0.33) | TDP1KEAP1NFE2L2HCAR2 | |
| SCHEMBL8944205 | 1.00 | TDP1 (0.33) | TDP1KEAP1NFE2L2HCAR2 | |
| SCHEMBL10499808 | 0.81 | — | — | |
| SCHEMBL610325 | 0.77 | — | — | |
| SCHEMBL14150684 | 0.75 | — | — | |
| SCHEMBL932667 | 0.75 | — | — | |
| SCHEMBL11288089 | 0.75 | HCAR2 (0.38) | TDP1KEAP1NFE2L2HCAR2 | |
| SCHEMBL6938126 | 0.71 | HCAR2 (0.42) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL28854777 | 0.70 | MAPT (0.34) | — | |
| SCHEMBL17159774 | 0.69 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576054-A | ULTRAVIOLET RESISTANT OPAQUE GLASS COATING | GENERAL ELECTRIC COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0234720-B1 | SILICONE RUBBER COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |
| EP-0234720-A1 | Silicone rubber compositions | GENERAL ELECTRIC COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |