SCHEMBL8944240

SCHEMBL8944240

CCOc1ccc(N(c2ccc(O)cc2)c2ccc(OCC)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.70
NQO1 P15559 1/20 0.58
NR5A1 Q13285 1/20 0.50
MAOB P27338 1/20 0.49
ABCG2 Q9UNQ0 1/20 0.49
TSHR P16473 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
PARP10 Q53GL7 1/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPT P10636 2/20 0.44
ADRA2A P08913 1/20 0.44
LMNA P02545 2/20 0.44
MAPK1 P28482 1/20 0.44
CYP1A2 P05177 1/20 0.44
PTGS1 P23219 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Hydroxy-4-Ethoxybenzene SCHEMBL28520 0.89 LTA4H (0.86) LTA4HNQO1NR5A1MAOBABCG2
1-Hydroxy-4-Ethoxybenzene SCHEMBL12476725 0.89 LTA4H (0.86) LTA4HNQO1NR5A1MAOBABCG2
SCHEMBL3239122 0.89 NQO1 (0.74) LTA4HNQO1TSHRTDP1ALDH1A1
1-Hydroxy-4-Ethoxybenzene SCHEMBL8054038 0.87 LTA4H (0.83) LTA4HNQO1NR5A1MAOBABCG2
1-Hydroxy-4-Ethoxybenzene SCHEMBL28372944 0.87 LTA4H (0.83) LTA4HNQO1NR5A1MAOBABCG2
1-Hydroxy-4-Ethoxybenzene SCHEMBL10831800 0.87 LTA4H (0.83) LTA4HNQO1NR5A1MAOBABCG2
1-Hydroxy-4-Ethoxybenzene SCHEMBL27361340 0.87 LTA4H (0.83) LTA4HNQO1NR5A1MAOBABCG2
SCHEMBL7448357 0.83 LTA4H (0.76) LTA4HNQO1NR5A1MAOBABCG2
SCHEMBL10704555 0.83 LTA4H (0.76) LTA4HNQO1NR5A1MAOBABCG2
SCHEMBL8943785 0.83 LTA4H (0.65) LTA4HNQO1TSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed