SCHEMBL8944267

SCHEMBL8944267

COc1ccc(N(c2ccc(OC)cc2)c2cccc(N(c3ccc(OC)cc3)c3ccc(OC)cc3)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA12 O43570 1/20 0.48
CA14 Q9ULX7 1/20 0.48
ENPP2 Q13822 2/20 0.44
APP P05067 1/20 0.43
SLC2A1 P11166 1/20 0.42
ABL1 P00519 1/20 0.42
ABCB1 P08183 1/20 0.42
BCR P11274 1/20 0.42
CA4 P22748 1/20 0.42
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
LTA4H P09960 1/20 0.41
RELA Q04206 2/20 0.41
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
ACHE P22303 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10065628 0.96 CA4 (0.50) CA1CA2CA7CA9CA12
SCHEMBL8944101 0.92 HSD17B2 (0.50) CA1CA2CA7CA9CA12
SCHEMBL13020925 0.89 CA4 (0.52) CA1CA2CA7CA9CA12
SCHEMBL14163850 0.89 CA4 (0.52) CA1CA2CA7CA9CA12
SCHEMBL14163846 0.89 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL13385303 0.88 CA4 (0.52) ENPP2CA4HSD17B1HSD17B2LTA4H
SCHEMBL8944301 0.88 HSD17B1 (0.51) CA1CA2CA7CA9CA12
SCHEMBL14158330 0.88 ACHE (0.53) CA1CA2CA7CA9CA12
SCHEMBL10065391 0.88 NPC1 (0.51) CA4LTA4HRELAMTNR1AMTNR1B
SCHEMBL14163837 0.87 ACHE (0.50) CA1CA2CA7CA9ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed