SCHEMBL8944274

SCHEMBL8944274

Oc1cnc2nn[nH]c2c1

nearest known ligand 0.31

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.31
DYRK1B Q9Y463 2/20 0.31
FGFR1 P11362 1/20 0.31
FGFR2 P21802 1/20 0.31
FGFR3 P22607 1/20 0.31
DYRK3 O43781 1/20 0.30
CSNK1E P49674 1/20 0.30
CLK1 P49759 1/20 0.30
CLK2 P49760 1/20 0.30
CLK3 P49761 1/20 0.30
GSK3B P49841 1/20 0.30
CDK5 Q00535 1/20 0.30
CDK5R1 Q15078 1/20 0.30
DYRK2 Q92630 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30
DYRK4 Q9NR20 1/20 0.30
CHEK1 O14757 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL917562 0.77 HTT (0.42) DYRK1A
SCHEMBL23092892 0.75 KDM4E (0.38) DYRK1ADYRK1BFGFR1CLK2CDK5
SCHEMBL12746195 0.75 AURKA (0.37)
SCHEMBL732343 0.75 SMN1; SMN2 (0.47) DYRK1ADYRK1BFGFR1CLK2GSK3B
SCHEMBL30274994 0.75 ENPP2 (0.31)
SCHEMBL14121253 0.73 HCAR2 (0.39) DYRK1B
SCHEMBL18687135 0.71 CYP3A4 (0.36)
SCHEMBL14234592 0.71 ALDH1A1 (0.30)
SCHEMBL3986771 0.70
SCHEMBL30274941 0.69 ALDH1A1 (0.40) DYRK1ADYRK1BFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480716-A MULTILAYER ELEMENT WITH SUPPORT AND MAGNETIC LAYER WITH FERROMAGNETIC METALS FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed