Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944334 | 0.91 | S1PR4 (0.43) | NPC1RAB9ARECQLS1PR4TDP1 | |
| SCHEMBL11414367 | 0.78 | TSHR (0.43) | NPC1RAB9ARECQLTDP1TSHR | |
| SCHEMBL10885884 | 0.77 | MERTK (0.46) | NPC1RAB9ARECQLS1PR4TDP1 | |
| SCHEMBL10744505 | 0.75 | CTSV (0.50) | NPC1RAB9ARECQLCYP11B1CYP11B2 | |
| SCHEMBL6815549 | 0.75 | MAPT (0.49) | NPC1RAB9AS1PR4TDP1TSHR | |
| SCHEMBL10884859 | 0.74 | TSHR (0.48) | NPC1RAB9ARECQLS1PR4CYP11B1 | |
| SCHEMBL8944451 | 0.74 | NPC1 (0.49) | NPC1RAB9ARECQLCYP11B1CYP11B2 | |
| SCHEMBL3351038 | 0.73 | PIN1 (0.49) | NPC1RAB9ACYP11B1CYP11B2MAPT | |
| SCHEMBL5098363 | 0.73 | S1PR4 (0.50) | NPC1RAB9ARECQLS1PR4CYP11B1 | |
| SCHEMBL6814271 | 0.72 | MAPT (0.47) | NPC1RAB9AS1PR4ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5503640-A | ALKYLTHIO PARA-AMINOPHENOLS IN AQUEOUS VEHICLE FOR DYEING HUMAN HAIR | L'OREAL (FR) | 1996-04-02 | — | — | US | disclosed |
| US-5364413-A | Oxidation color dyes for hair | L'OREAL (FR) | 1994-11-15 | — | — | US | disclosed |
| US-5084067-A | Indoaniline dyes for hair dyes | L'OREAL (FR) | 1992-01-28 | — | — | US | disclosed |