SCHEMBL8944369

SCHEMBL8944369

O=C(CCCC1CCCCC1)C(=O)CCCC1CCCC1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
HPGD P15428 1/20 0.48
SIGMAR1 Q99720 3/20 0.46
KDM5A P29375 3/20 0.46
PHF8 Q9UPP1 3/20 0.46
KDM2A Q9Y2K7 3/20 0.46
KDM4C Q9H3R0 2/20 0.46
KDM4A O75164 1/20 0.46
EPHX1 P07099 1/20 0.44
P2RX7 Q99572 1/20 0.43
NAAA Q02083 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8395272 0.91 KDM5A (0.40) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL3020223 0.89 KDM5A (0.46) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL11438858 0.86 CYP1A2 (0.50) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL27934108 0.85 HPGD (0.57) CYP1A2HPGDEPHX1NPC1RAB9A
SCHEMBL15263567 0.85 CYP1A2 (0.45) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL6436051 0.85 CYP1A2 (0.45) CYP1A2HPGDSIGMAR1KDM5APHF8
Potassium Ion SCHEMBL3886712 0.85 CYP1A2 (0.45) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL22598033 0.85 CYP1A2 (0.45) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL22418773 0.85 CYP1A2 (0.45) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL5013210 0.85 CYP1A2 (0.45) CYP1A2HPGDSIGMAR1KDM5APHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541229-A ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1996-07-30 US disclosed