Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944369 | 0.91 | CYP1A2 (0.50) | KDM5APHF8KDM2AKDM4CHPGD | |
| SCHEMBL10587895 | 0.81 | KDM5A (0.40) | KDM5APHF8KDM2AKDM4CHPGD | |
| SCHEMBL4361532 | 0.81 | KDM5A (0.51) | KDM5APHF8KDM2AKDM4CHPGD | |
| SCHEMBL8392784 | 0.81 | ALOX5 (0.43) | KDM5APHF8KDM2AKDM4CHPGD | |
| SCHEMBL3020223 | 0.80 | KDM5A (0.46) | KDM5APHF8KDM2AKDM4CHPGD | |
| SCHEMBL8392779 | 0.79 | KDM5A (0.39) | KDM5APHF8KDM2AKDM4CHPGD | |
| SCHEMBL10585122 | 0.79 | KDM5A (0.39) | KDM5APHF8KDM2AKDM4CHPGD | |
| SCHEMBL10585125 | 0.79 | KDM5A (0.39) | KDM5APHF8KDM2AKDM4CHPGD | |
| SCHEMBL28835644 | 0.77 | KDM5A (0.41) | KDM5APHF8KDM2AKDM4CHPGD | |
| SCHEMBL11438858 | 0.76 | CYP1A2 (0.50) | KDM5APHF8KDM2AKDM4CHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |