Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548489 | 0.79 | LTB4R2 (0.49) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL8548764 | 0.74 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL8551839 | 0.72 | LTB4R2 (0.42) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL8549165 | 0.70 | LTB4R2 (0.48) | LTB4R2AGTR1 | |
| SCHEMBL6605207 | 0.68 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8552550 | 0.67 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL8548756 | 0.67 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL8944180 | 0.66 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL8549173 | 0.66 | LTB4R2 (0.53) | LTB4R2AGTR1 | |
| SCHEMBL8553682 | 0.65 | LTB4R2 (0.49) | LTB4R2AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500427-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-19 | — | — | US | disclosed |