SCHEMBL8944180

SCHEMBL8944180

CCCN(c1ccc(-c2ccccc2-c2nc(=O)o[nH]2)cc1)c1ncccc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 17/20 0.49
AGTR2 P50052 17/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6609591 0.83 AGTR1 (0.66) AGTR1AGTR2
SCHEMBL8944173 0.75 KDM4E (0.40) AGTR1AGTR2
SCHEMBL6606977 0.74 AGTR1 (0.67) AGTR1AGTR2
SCHEMBL6608938 0.74 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL8548764 0.73 AGTR1 (0.65) AGTR1AGTR2
SCHEMBL6607142 0.73 BRS3 (0.39) AGTR1AGTR2
SCHEMBL6607561 0.71 AGTR1 (0.66) AGTR1AGTR2
SCHEMBL8552550 0.71 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL2512493 0.70 AGTR2 (0.51) AGTR1AGTR2
SCHEMBL6623911 0.70 AGTR1 (0.65) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5500427-A ANGIOTENSIN II ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-03-19 US claimed