Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | CCR5 | P51681 | 1/20 | 0.62 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31648790 | 0.87 | CCR1 (0.56) | CCR1RAB9ACCR5PARP1MAPT | |
| SCHEMBL8944345 | 0.87 | CCR1 (0.56) | CCR1RAB9ACCR5PARP1MAPT | |
| SCHEMBL13826732 | 0.81 | CCR1 (0.65) | CCR1RAB9ACCR5METAP2PARP1 | |
| SCHEMBL8944167 | 0.79 | CCR1 (0.75) | CCR1RAB9ACCR5METAP2PARP1 | |
| SCHEMBL14732999 | 0.79 | CCR1 (0.62) | CCR1RAB9ACCR5METAP2PARP1 | |
| Neocuproine SCHEMBL29367091 | 0.79 | CCR1 (1.00) | CCR1RAB9ACCR5METAP2PARP1 | |
| Neocuproine SCHEMBL124563 | 0.79 | CCR1 (1.00) | CCR1RAB9ACCR5METAP2PARP1 | |
| Neocuproine SCHEMBL29639703 | 0.79 | CCR1 (1.00) | CCR1RAB9ACCR5METAP2PARP1 | |
| Neocuproine SCHEMBL11672280 | 0.79 | CCR1 (1.00) | CCR1RAB9ACCR5METAP2PARP1 | |
| SCHEMBL8181932 | 0.78 | CCR1 (0.39) | CCR1RAB9ACCR5PARP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545639-A | USING 2,9-BIS(HALOMETHYL)-1,10-PHENANTHROLINE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-08-13 | — | — | US | disclosed |