SCHEMBL8944167

SCHEMBL8944167

Cc1ccc2ccc3ccc(CBr)nc3c2n1

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.75
RAB9A P51151 1/20 0.62
CCR5 P51681 1/20 0.62
METAP2 P50579 1/20 0.42
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
PARP1 P09874 1/20 0.37
KDM4E B2RXH2 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
GLO1 Q04760 2/20 0.35
CYP1A2 P05177 3/20 0.34
OPRK1 P41145 1/20 0.33
BDKRB2 P30411 1/20 0.33
AGTR1 P30556 1/20 0.32
PAX8 Q06710 1/20 0.32
SLC40A1 Q9NP59 1/20 0.32
PDE10A Q9Y233 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1258482 0.87 CCR1 (1.00) CCR1RAB9ACCR5PARP1KDM4E
SCHEMBL14732999 0.83 CCR1 (0.62) CCR1RAB9ACCR5METAP2KMT2A
SCHEMBL13826732 0.81 CCR1 (0.65) CCR1RAB9ACCR5METAP2KMT2A
SCHEMBL8944463 0.79 CCR1 (0.62) CCR1RAB9ACCR5METAP2KMT2A
Neocuproine SCHEMBL29639703 0.79 CCR1 (1.00) CCR1RAB9ACCR5METAP2KMT2A
Neocuproine SCHEMBL124563 0.79 CCR1 (1.00) CCR1RAB9ACCR5METAP2KMT2A
Neocuproine SCHEMBL29367091 0.79 CCR1 (1.00) CCR1RAB9ACCR5METAP2KMT2A
Neocuproine SCHEMBL11672280 0.79 CCR1 (1.00) CCR1RAB9ACCR5METAP2KMT2A
SCHEMBL10699170 0.79 CCR1 (0.56) CCR1RAB9ACCR5METAP2KMT2A
Neocuproine SCHEMBL8636520 0.79 CCR1 (0.56) CCR1RAB9ACCR5METAP2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724856-B Europium complex and preparation method and application thereof 华东理工大学 2024-04-12 CN disclosed
CN-114436949-B Tetradentate ligand, metal complex, and preparation methods and applications thereof 上海巽田科技股份有限公司 2023-09-22 CN disclosed
CN-115724856-A Europium complex and preparation method and application thereof 华东理工大学 2023-03-03 CN disclosed
CN-114436949-A Tetradentate ligand and metal complex, and preparation method and application thereof 上海巽田科技股份有限公司 2022-05-06 CN disclosed
US-5545639-A USING 2,9-BIS(HALOMETHYL)-1,10-PHENANTHROLINE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-08-13 US disclosed
US-4859777-A Terpyridine chelating agents EASTMAN KODAK COMPANY (US) 1989-08-22 US disclosed
US-4837169-A RADIOIMMUNOASSAY EASTMAN KODAK COMPANY (US) 1989-06-06 US disclosed
EP-0288256-A2 Fluorescent labels EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-10-26 EP disclosed