Neocuproine

Neocuproine

SCHEMBL29639703

Cc1ccc2ccc3ccc(C)nc3c2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCR1 P32246 2/20 1.00
▸ RAB9A P51151 1/20 1.00
▸ CCR5 P51681 1/20 1.00
▸ METAP2 P50579 1/20 0.58
▸ PARP1 P09874 1/20 0.48
▸ CYP1A2 P05177 3/20 0.48
▸ GLO1 Q04760 2/20 0.45
▸ KMT2A Q03164 5/20 0.44
▸ OPRK1 P41145 1/20 0.44
▸ CCR8 P51685 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ CASP6 P55212 1/20 0.41
▸ MEN1 O00255 4/20 0.40
▸ SLC40A1 Q9NP59 2/20 0.40
▸ AGTR1 P30556 1/20 0.40
▸ PAX8 Q06710 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Neocuproine SCHEMBL29367091 1.00 CCR1 (1.00) CCR1RAB9ACCR5METAP2PARP1
Neocuproine SCHEMBL11672280 1.00 CCR1 (1.00) CCR1RAB9ACCR5METAP2PARP1
Neocuproine SCHEMBL124563 1.00 CCR1 (1.00) CCR1RAB9ACCR5METAP2PARP1
Neocuproine SCHEMBL31709522 0.97 CCR1 (0.94) CCR1RAB9ACCR5METAP2PARP1
Neocuproine SCHEMBL870750 0.97 CCR1 (0.94) CCR1RAB9ACCR5METAP2PARP1
Neocuproine SCHEMBL17926728 0.97 CCR1 (0.94) CCR1RAB9ACCR5METAP2PARP1
Neocuproine SCHEMBL229136 0.97 CCR1 (0.94) CCR1RAB9ACCR5METAP2PARP1
Neocuproine SCHEMBL1462062 0.97 CCR1 (0.94) CCR1RAB9ACCR5METAP2PARP1
Neocuproine SCHEMBL5385744 0.97 CCR1 (0.94) CCR1RAB9ACCR5METAP2PARP1
Neocuproine SCHEMBL10373258 0.97 CCR1 (0.94) CCR1RAB9ACCR5METAP2PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062381-A1 METHODS FOR SYNTHESIS OF THE TRICYCLIC PROSTAGLANDIN D2 METABOLITE METHYL ESTER PURDUE RESEARCH FOUNDATION 2026-03-05 — — US claimed
EP-4632063-A2 COPPER LOSS MITIGATION GENENTECH, INC. (US) 2025-10-15 — — EP claimed
EP-4136211-B1 COPPER LOSS MITIGATION GENENTECH INC (US) 2025-07-09 — — EP claimed
EP-3710837-B1 CATHINONE TEST UNIV SYDNEY TECHNOLOGY (AU) 2025-05-07 — — EP claimed
US-20230174477-A1 METHODS FOR SYNTHESIS OF THE TRICYCLIC PROSTAGLANDIN D2 METABOLITE METHYL ESTER PURDUE RESEARCH FOUNDATION 2023-06-08 — — US claimed
EP-4136211-A1 COPPER LOSS MITIGATION Genentech, Inc. (US) 2023-02-22 — — EP claimed
EP-3500572-B1 CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION UNIV BRISTOL (GB) 2022-10-26 — — EP claimed
US-12630834-B2 Methods and compositions for regulating alkaloids in tobacco ALTRIA CLIENT SERVICES LLC (US) 2026-05-19 — — US disclosed
US-20260125272-A1 ZEOLITIC MATERIALS AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-07 — — US disclosed
US-20260117236-A1 METHODS AND COMPOSITIONS FOR MODULATING TRICHOME DENSITY AND FLAVOR MOLECULE SECRETION ALTRIA CLIENT SERVICES LLC (US) 2026-04-30 — — US disclosed
US-12606840-B2 Compositions and methods for producing tobacco plants and products having altered alkaloid levels with desirable leaf quality ALTRIA CLIENT SERVICES LLC (US) 2026-04-21 — — US disclosed
US-12590315-B2 Compositions and methods based on QPT engineering for producing tobacco plants and products having altered alkaloid levels ALTRIA CLIENT SERVICES LLC (US) 2026-03-31 — — US disclosed
US-12575536-B2 Compositions and methods for producing tobacco plants and products having altered alkaloid levels ALTRIA CLIENT SERVICES LLC (US) 2026-03-17 — — US disclosed
WO-2022187845-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2022-09-09 — — WO disclosed
EP-4041899-A1 COMPOSITIONS AND METHODS BASED ON QPT ENGINEERING FOR PRODUCING TOBACCO PLANTS AND PRODUCTS HAVING ALTERED ALKALOID LEVELS Altria Client Services LLC (US) 2022-08-17 — — EP disclosed
EP-4041898-A1 COMPOSITIONS AND METHODS FOR PRODUCING TOBACCO PLANTS AND PRODUCTS HAVING ALTERED ALKALOID LEVELS WITH DESIRABLE LEAF QUALITY VIA MANIPULATING LEAF QUALITY GENES Altria Client Services LLC (US) 2022-08-17 — — EP disclosed
US-11384361-B2 Compositions and methods based on PMT engineering for producing tobacco plants and products having altered alkaloid levels ALTRIA CLIENT SERVICES LLC (US) 2022-07-12 — — US disclosed
US-20220204981-A1 COMPOSITIONS AND METHODS FOR PRODUCING TOBACCO PLANTS AND PRODUCTS HAVING ALTERED ALKALOID LEVELS WITH DESIRABLE LEAF QUALITY ALTRIA CLIENT SERVICES LLC (US) 2022-06-30 — — US disclosed
US-11351155-B2 Compositions and methods of modulating s-nitrosylation CASE WESTERN RESERVE UNIVERSITY (US) 2022-06-07 — — US disclosed
WO-2022102226-A1 ELECTROLESS COPPER PLATING SOLUTION メルテックス株式会社 2022-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125272-A1 ZEOLITIC MATERIALS AND METHODS OF MAKING AND USING THEREOF MIF, CA1, CLK1 CCR1 403/4885RAB9A 1327/4885CCR5 1700/4885
US-12606840-B2 Compositions and methods for producing tobacco plants and products having altered alkaloid levels with desirable leaf quality ODC1, NOS2, NOS1 CCR1 4587/4885RAB9A 3079/4885CCR5 3576/4885
US-12630834-B2 Methods and compositions for regulating alkaloids in tobacco UPF1, SET, WAPL CCR1 4721/4885RAB9A 3342/4885CCR5 4147/4885
US-12575536-B2 Compositions and methods for producing tobacco plants and products having altered alkaloid levels UPF1, EDNRB, EDF1 CCR1 4566/4885RAB9A 1643/4885CCR5 3304/4885
US-20260117236-A1 METHODS AND COMPOSITIONS FOR MODULATING TRICHOME DENSITY AND FLAVOR MOLECULE SECRETION TAS2R50, TAS2R30, TAS2R31 CCR1 4751/4885RAB9A 518/4885CCR5 4399/4885
US-12590315-B2 Compositions and methods based on QPT engineering for producing tobacco plants and products having altered alkaloid levels NAPRT, HPRT1, NMT2 CCR1 4621/4885RAB9A 468/4885CCR5 3843/4885
US-20230174477-A1 METHODS FOR SYNTHESIS OF THE TRICYCLIC PROSTAGLANDIN D2 METABOLITE METHYL ESTER PTGES2, PTGDR2, PTGES CCR1 3006/4885RAB9A 4390/4885CCR5 2139/4885
US-11351155-B2 Compositions and methods of modulating s-nitrosylation AKR1A1, AKR1B1, AKR1C2 CCR1 4831/4885RAB9A 2208/4885CCR5 4720/4885
US-20260062381-A1 METHODS FOR SYNTHESIS OF THE TRICYCLIC PROSTAGLANDIN D2 METABOLITE METHYL ESTER PTGDR2, PTGDR, PTGES2 CCR1 3849/4885RAB9A 4025/4885CCR5 2819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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