Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954088 | 0.86 | ALDH1A1 (0.45) | ALDH1A1CYP3A4GPR35PDE7ASLC6A4 | |
| SCHEMBL9525231 | 0.86 | ALDH1A1 (0.45) | ALDH1A1CYP3A4GPR35PDE7ASLC6A4 | |
| SCHEMBL6370768 | 0.85 | PDE7A (0.53) | ALDH1A1CYP3A4GPR35PDE7ASLC6A4 | |
| SCHEMBL8447032 | 0.81 | SLC6A4 (0.53) | ALDH1A1CYP3A4PDE7ASLC6A4TSHR | |
| SCHEMBL8781111 | 0.80 | SNCA (0.44) | ALDH1A1CYP3A4GPR35TSHRMAPK1 | |
| SCHEMBL9525225 | 0.78 | CA2 (0.45) | ALDH1A1CYP3A4GPR35PDE7ASLC6A4 | |
| SCHEMBL5642359 | 0.77 | ALDH1A1 (0.63) | ALDH1A1CYP3A4GPR35TSHRMAPK1 | |
| SCHEMBL6371711 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CYP3A4PDE7AMAPK1SMN1; SMN2 | |
| SCHEMBL6156287 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP3A4GPR35TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL8944452 | 0.76 | CA2 (0.44) | ALDH1A1CYP3A4GPR35PDE7ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331144-B1 | 3-SUBSTITUTED PARA-AMINO PHENOLS, PROCESS FOR THEIR PREPARATION, THEIR USE IN DYEING KERATENIC FIBRES AND INTERMEDIATES USED IN THE PREPARATION PROCESS | L'OREAL (FR) | 1993-06-09 | — | — | EP | claimed |
| US-5503640-A | ALKYLTHIO PARA-AMINOPHENOLS IN AQUEOUS VEHICLE FOR DYEING HUMAN HAIR | L'OREAL (FR) | 1996-04-02 | — | — | US | disclosed |
| US-5364413-A | Oxidation color dyes for hair | L'OREAL (FR) | 1994-11-15 | — | — | US | disclosed |
| US-5084067-A | Indoaniline dyes for hair dyes | L'OREAL (FR) | 1992-01-28 | — | — | US | disclosed |