Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396174 | 0.98 | EPHX1 (0.51) | EPHX1HRH4HRH3SIGMAR1BCHE | |
| SCHEMBL8397097 | 0.98 | EPHX1 (0.51) | EPHX1HRH4HRH3SIGMAR1BCHE | |
| SCHEMBL8397005 | 0.96 | EPHX1 (0.45) | EPHX1HRH4HRH3SIGMAR1BCHE | |
| SCHEMBL8395535 | 0.93 | HRH4 (0.45) | EPHX1HRH4HRH3L3MBTL1GLA | |
| SCHEMBL8396767 | 0.90 | HRH4 (0.49) | EPHX1HRH4HRH3SIGMAR1ACHE | |
| SCHEMBL8392734 | 0.88 | HRH4 (0.51) | EPHX1HRH4HRH3SIGMAR1L3MBTL1 | |
| SCHEMBL8396985 | 0.88 | HRH4 (0.51) | EPHX1HRH4HRH3SIGMAR1L3MBTL1 | |
| SCHEMBL8393995 | 0.86 | HRH4 (0.46) | EPHX1HRH4HRH3SIGMAR1ACHE | |
| SCHEMBL8111965 | 0.85 | HRH4 (0.40) | EPHX1HRH4HRH3L3MBTL1GLA | |
| SCHEMBL8972147 | 0.85 | TPSAB1 (0.45) | EPHX1HRH4HRH3SIGMAR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |