Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.71 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.71 |
| ▸ | PPARG | P37231 | 8/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8905204 | 1.00 | AGTR1 (0.71) | AGTR1AGTR2PPARG | |
| SCHEMBL8395423 | 0.95 | AGTR1 (0.79) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL8944849 | 0.93 | AGTR1 (0.71) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL8394597 | 0.89 | AGTR1 (0.69) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL8395901 | 0.88 | AGTR1 (0.68) | AGTR1AGTR2PPARG | |
| SCHEMBL9095466 | 0.88 | AGTR1 (0.59) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9042017 | 0.88 | AGTR1 (0.54) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL8790364 | 0.88 | AGTR1 (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL8391692 | 0.87 | AGTR1 (0.83) | AGTR1AGTR2PPARG | |
| SCHEMBL7054367 | 0.86 | AGTR1 (0.82) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |