Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8790364 | 1.00 | AGTR1 (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL8788433 | 0.95 | AGTR1 (0.59) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9040471 | 0.94 | AGTR1 (0.54) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9040536 | 0.89 | AGTR1 (0.53) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9041973 | 0.89 | AGTR1 (0.56) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL8905204 | 0.88 | AGTR1 (0.71) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL8944516 | 0.88 | AGTR1 (0.71) | AGTR1AGTR2PPARG | |
| SCHEMBL9042283 | 0.87 | AGTR1 (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL8789884 | 0.86 | AGTR1 (0.55) | AGTR1AGTR2PPARG | |
| SCHEMBL9042345 | 0.86 | AGTR1 (0.58) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |