SCHEMBL8944534

SCHEMBL8944534

COC(=O)CCC(=O)Nc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.60
ALDH1A1 P00352 4/20 0.58
GAA P10253 4/20 0.58
TDP1 Q9NUW8 1/20 0.58
VCAM1 P19320 1/20 0.53
HTT P42858 2/20 0.53
HPGD P15428 1/20 0.53
PTPRC P08575 2/20 0.51
CTSL P07711 1/20 0.51
PTPN13 Q12923 1/20 0.51
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
POLB P06746 1/20 0.45
PTGS1 P23219 1/20 0.45
TYMS P04818 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944807 0.88 GAA (0.53) L3MBTL1ALDH1A1GAATDP1VCAM1
SCHEMBL9812401 0.86 GAA (0.60) L3MBTL1ALDH1A1GAATDP1VCAM1
SCHEMBL9575165 0.84 GAA (0.70) L3MBTL1ALDH1A1GAATDP1KMT2A
SCHEMBL11798744 0.84 ALDH1A1 (0.58) L3MBTL1ALDH1A1GAATDP1VCAM1
SCHEMBL1410855 0.84 GAA (0.62) L3MBTL1ALDH1A1GAATDP1KMT2A
SCHEMBL29282569 0.84 ALDH1A1 (0.62) ALDH1A1GAATDP1HPGDPTPRC
SCHEMBL10598165 0.83 ALDH1A1 (0.60) ALDH1A1GAATDP1VCAM1KMT2A
SCHEMBL11702602 0.83 GAA (0.72) ALDH1A1GAATDP1HTTKMT2A
SCHEMBL11652025 0.83 GAA (0.60) ALDH1A1GAATDP1VCAM1KMT2A
SCHEMBL3483031 0.80 GAA (0.66) ALDH1A1GAATDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5578731-A ASYMMETRICAL HYDRAZINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1996-11-26 US disclosed
US-5554754-A PHOTOSTABILIZERS CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
US-5470980-A Light stabilizers for polymers that can be grafted to polymers CIBA-GEIGY CORPORATION (US) 1995-11-28 US disclosed
EP-0647626-A1 Azadicarboxylic acid derivatives containing hindered amine moieties as polymer stabilisers CIBA-GEIGY AG (CH) 1995-04-12 EP disclosed
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5352719-A Blended with synthetic or natural polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-10-04 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed
US-5319090-A Benzotriazole and oxanilide UV absorber hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-06-07 US disclosed
US-5233047-A Benzotriazole UV absorber hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-08-03 US disclosed
US-5116976-A HINDERED AMINE LIGHT STABILIZER HYDRAZIDES ATOCHEM NORTH AMERICA, INC (US) 1992-05-26 US disclosed
EP-0467344-A1 Hindered amine light stabilizer hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-01-22 EP disclosed
US-5041545-A 2-hydroxybenzophenone hydrazides and derivatives thereof ATOCHEM NORTH AMERICA, INC. (US) 1991-08-20 US disclosed
US-4980420-A Benzotriazole and oxanilide UV absorber hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1990-12-25 US disclosed