SCHEMBL8944544

SCHEMBL8944544

O=C(O)c1ccc2cccc(O)c2c1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
ALDH1A1 P00352 4/20 0.53
KMT2A Q03164 3/20 0.53
HSD17B10 Q99714 2/20 0.53
MEN1 O00255 2/20 0.53
TSHR P16473 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
GRIN2D O15399 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
LDHA P00338 1/20 0.46
HMGB1 P09429 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30355326 0.85 HSD17B10 (0.62) KDM4EALDH1A1KMT2AHSD17B10MEN1
SCHEMBL3392195 0.85 CA12 (0.61) KDM4EALDH1A1KMT2AHSD17B10MEN1
SCHEMBL3683209 0.85 HSD17B10 (0.62) KDM4EALDH1A1KMT2AHSD17B10MEN1
SCHEMBL31401777 0.85 HSD17B10 (0.62) KDM4EALDH1A1KMT2AHSD17B10MEN1
SCHEMBL3389763 0.83 ALDH1A1 (0.69) KDM4EALDH1A1KMT2AHSD17B10MEN1
SCHEMBL9137723 0.82 CYP1A2 (0.55) KDM4EALDH1A1KMT2AHSD17B10MEN1
SCHEMBL3447012 0.82 CYP1A2 (0.55) KDM4EALDH1A1KMT2AHSD17B10MEN1
SCHEMBL12486671 0.81 HSD17B10 (0.62) KDM4EALDH1A1KMT2AHSD17B10MEN1
SCHEMBL689259 0.80 HSD17B10 (0.67) KDM4EALDH1A1KMT2AHSD17B10MEN1
SCHEMBL29940636 0.80 HSD17B10 (0.67) KDM4EALDH1A1KMT2AHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523337-A CURABLE THERMOSETTING RESIN COMPRISING UNSATURATED ESTER, OLEFIN MONOMER, LOW PROFILE ADDITIVE, MOLD RELEASE AGENT, AND BLOCK COPOLYMER OF UNSATURATED POLYESTER AND DIISOCYANATE FUNCTIONAL POLYMER; STRESS RESISTANCE GENCORP INC. (US) 1996-06-04 US disclosed
US-5498763-A NONCRACKING GENCORP INC. (US) 1996-03-12 US disclosed
US-5491184-A MIXING COMPATIBLE BLOCK COPOLYMER INTO UNSATURATED POLYESTER RESIN COMPOSITION TO TOUGHEN GENCORP. INC. (US) 1996-02-13 US disclosed
EP-0662501-A1 Polymeric compositions, their preparation and use GENCORP INC. (US) 1995-07-12 EP disclosed
US-5428068-A Addition-condensation block polymers GENCORP INC. (US) 1995-06-27 US disclosed
US-5389443-A Improved elongation, flexibility; for fiber reinforced plastics GENCORP INC. (US) 1995-02-14 US disclosed
US-5385963-A Unsaturated polyester-modified flexible copolymers for use in sheet molding compositions GENCORP INC. (US) 1995-01-31 US disclosed
US-5362819-A Polyester-flexible polymer block copolymers and mixtures thereof GENCORP INC. (US) 1994-11-08 US disclosed
EP-0612786-A1 Polyester-flexible polymer block copolymers and mixtures thereof GENCORP INC. (US) 1994-08-31 EP disclosed
EP-0612787-A1 Polyester-flexible polymer block copolymer coated fiber structures and utilization thereof in a polymer matrix GENCORP INC. (US) 1994-08-31 EP disclosed
US-5334441-A Tough, noncracking, flexible sheet molding materials, for automobile panels, aircraft, housings GENCORP INC. (US) 1994-08-02 US disclosed