Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.68 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.56 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11094774 | 0.98 | SIGMAR1 (0.66) | SIGMAR1TMEM97MEN1KMT2ATDP1 | |
| SCHEMBL11117998 | 0.85 | CARM1 (0.56) | SIGMAR1TMEM97CARM1PRMT6PRMT8 | |
| SCHEMBL13991801 | 0.85 | CARM1 (0.56) | SIGMAR1TMEM97CARM1PRMT6PRMT8 | |
| SCHEMBL11117996 | 0.84 | CARM1 (0.55) | SIGMAR1TMEM97CARM1PRMT6PRMT8 | |
| SCHEMBL17465600 | 0.84 | MEN1 (0.55) | SIGMAR1TMEM97MEN1KMT2ATDP1 | |
| SCHEMBL133622 | 0.82 | MEN1 (0.64) | SIGMAR1TMEM97MEN1KMT2ATDP1 | |
| SCHEMBL16081555 | 0.82 | CARM1 (0.53) | SIGMAR1TMEM97CARM1PRMT6PRMT8 | |
| SCHEMBL17372404 | 0.81 | SIGMAR1 (1.00) | SIGMAR1TMEM97TDP1MAOACHRM2 | |
| SCHEMBL1268109 | 0.81 | CARM1 (0.60) | SIGMAR1TMEM97CARM1PRMT6PRMT8 | |
| Ammonia Solution, Strong SCHEMBL16268586 | 0.81 | MEN1 (0.61) | SIGMAR1TMEM97MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448776-A | Method of using certain substituted aliphatic secondary amines or their salts for easing breathing | BUCHER KARL (CH) | 1984-05-15 | — | — | US | claimed |
| EP-3452556-B1 | COMPOSITION FOR FORMING DENSE SILICEOUS FILM | AZ ELECTRONIC MAT LUXEMBOURG SARL (LU) | 2020-04-15 | — | — | EP | disclosed |
| US-10563093-B2 | Composition for forming dense siliceous film | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) | 2020-02-18 | — | — | US | disclosed |
| US-20190136088-A1 | COMPOSITION FOR FORMING DENSE SILICEOUS FILM | AZ ELECTRONIC MATERIALS S.À R.L. (LU) | 2019-05-09 | — | — | US | disclosed |
| EP-3452556-A1 | COMPOSITION FOR FORMING DENSE SILICEOUS FILM | AZ Electronic Materials Luxembourg S.à.r.l. (LU) | 2019-03-13 | — | — | EP | disclosed |
| WO-2017191049-A1 | COMPOSITION FOR FORMING DENSE SILICEOUS FILM | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) | 2017-11-09 | — | — | WO | disclosed |
| EP-3124482-A1 | QUINOLINE DERIVATIVES AS SMO INHIBITORS | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-02-01 | — | — | EP | disclosed |
| EP-0638568-B1 | Substituted piperazines, their process of preparation and the pharmaceutical compositions containing them | ADIR (FR) | 1996-10-09 | — | — | EP | disclosed |
| US-5500426-A | ADMINISTERED TO IMPROVE GLUCOSE TOLERANCE | ADIR ET COMPAGNIE (FR) | 1996-03-19 | — | — | US | disclosed |
| US-5492912-A | IMPROVES GLUCOSE TOLERANCE | ADIR ET COMPAGNIE (FR) | 1996-02-20 | — | — | US | disclosed |
| EP-0638568-A1 | Substituted piperazines, their process of preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-02-15 | — | — | EP | disclosed |
| EP-0383089-B1 | Cold curing reactive resin blend and its use | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| US-5084544-A | Reaction of polyepoxides and polyisocyanates to form polyurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | disclosed |
| EP-0383089-A2 | Cold curing reactive resin blend and its use | BAYER AG (DE) | 1990-08-22 | — | — | EP | disclosed |
| US-4448776-A | Method of using certain substituted aliphatic secondary amines or their salts for easing breathing | BUCHER KARL (CH) | 1984-05-15 | — | — | US | disclosed |