SCHEMBL133622

SCHEMBL133622

CN(C)CCNCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
MAOA P21397 1/20 0.57
CHRM2 P08172 1/20 0.55
GAA P10253 1/20 0.55
MAPT P10636 1/20 0.55
TAAR1 Q96RJ0 1/20 0.54
SIGMAR1 Q99720 4/20 0.52
TMEM97 Q5BJF2 1/20 0.51
DRD4 P21917 1/20 0.48
VSIR Q9H7M9 1/20 0.48
HDAC1 Q13547 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL16268586 0.98 MEN1 (0.61) MEN1KMT2ATDP1MAOACHRM2
SCHEMBL10054980 0.89 SIGMAR1 (0.50) MEN1KMT2ATDP1CHRM2SIGMAR1
SCHEMBL1443953 0.88 MAOA (0.64) MEN1KMT2ATDP1MAOACHRM2
Hydrochloric Acid SCHEMBL21493579 0.86 MAOA (0.62) MEN1KMT2ATDP1MAOACHRM2
Methacrylic Acid SCHEMBL29650344 0.85 HDAC1 (0.48) MEN1KMT2ATDP1MAOACHRM2
SCHEMBL16151778 0.85 CHRM2 (0.63) MEN1KMT2ATDP1MAOACHRM2
Hydrochloric Acid SCHEMBL29778342 0.83 CHRM2 (0.61) MEN1KMT2ATDP1MAOACHRM2
SCHEMBL18615003 0.83 HDAC1 (0.46) MEN1KMT2ATDP1MAOACHRM2
SCHEMBL4502698 0.83 MEN1 (0.70) MEN1KMT2ATDP1MAOACHRM2
SCHEMBL8944637 0.82 SIGMAR1 (0.68) MEN1KMT2ATDP1MAOACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024154978-A1 AMPHIPATHIC POLYAMIDE-BASED REVERSE OSMOSIS SEPARATION MEMBRANE WITH IMPROVED FOULING RESISTANCE AND WEAR RESISTANCE AND MANUFACTURING METHOD THEREFOR 도레이첨단소재 주식회사 2024-07-25 WO claimed
CN-115943072-A Gas activated cyanoacrylates for 3D printing 汉高股份有限及两合公司 2023-04-07 CN claimed
US-20220002576-A1 GAS-ACTIVATED CYANOACRYLATES FOR 3-D PRINTING HENKEL AG & CO KGAA (DE) 2022-01-06 US claimed
EP-3708370-A1 3D-PRINTING METHOD USING GAS-ACTIVATED CYANOACRYLATES Henkel AG & Co. KGaA (DE) 2020-09-16 EP claimed
EP-3144072-A1 DISPENSER, KIT AND METHOD FOR APPLYING AN ACTIVATOR FOR A CURABLE CYANOACRYLATE-BASED COMPONENT Henkel AG & Co. KGaA (DE) 2017-03-22 EP claimed
US-7618912-B2 Preparation of supported catalyst systems BASELL POLYOLEFINE GMBH (DE) 2009-11-17 US claimed
EP-1144384-B1 COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARM INC (US) 2007-10-31 EP claimed
WO-2007006585-A2 SYNTHESIS OF A POROUS AND/OR STRATIFIED STRUCTURE MANGANESE OXIDE ELSPER RUEDIGER (DE) 2007-01-18 WO claimed
US-20060166813-A1 Preparation of supported catalyst systems BASELL POLYOLEFINE GMBH (DE) 2006-07-27 US claimed
US-20050113574-A1 Methods and compositions comprising diamines as new anti-tubercular therapeutics SEQUELLA, INC. 2005-05-26 US claimed
US-6479492-B1 TREATMENT OF INFLAMMATORY DISEASES IN A MAMMALIAN PATIENT ELAN PHARMACEUTICALS, INC. 2002-11-12 US claimed
US-6352810-B1 Toner coagulant processes XEROX CORPORATION 2002-03-05 US claimed
EP-0559835-B1 CONSUMER POLYOLEFIN PRIMER LOCTITE CORP (US) 1998-06-17 EP claimed
US-5314562-A Bonding a plastic substrate with an alpha-cyanoacrylate adhesive in which a primer comprising an ethylenediamine is used LOCTITE CORPORATION (US) 1994-05-24 US claimed
EP-0559835-A1 CONSUMER POLYOLEFIN PRIMER LOCTITE CORPORATION (US) 1993-09-15 EP claimed
WO-1992009669-A1 CONSUMER POLYOLEFIN PRIMER LOCTITE CORPORATION (US) 1992-06-11 WO claimed
EP-3474901-B1 CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION TAGWORKS PHARMACEUTICALS B V (NL) 2025-08-06 EP disclosed
US-12338226-B2 Substituted benzodiazoles and use thereof in therapy THOMAS HELLEDAYS STIFTELSE FOR MEDICINSK FORSKNING (SE) 2025-06-24 US disclosed
EP-0178947-A2 1-[(Aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl]-alpha,alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles A.H. ROBINS COMPANY, INCORPORATED (US) 1986-04-23 EP disclosed
US-4510082-A NONHABIT-FORMING ANALGESICS ELI LILLY AND COMPANY (US) 1985-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113574-A1 Methods and compositions comprising diamines as new anti-tubercular therapeutics C5, DDC, SAT1 MEN1 1886/4885KMT2A 2113/4885TDP1 716/4885
US-12338226-B2 Substituted benzodiazoles and use thereof in therapy XDH, CYP11B2, CYP4X1 MEN1 581/4885KMT2A 1639/4885TDP1 1726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.