SCHEMBL8944642

SCHEMBL8944642

CCCCCCCCON1C(C)(C)CC(OC(=O)NNC(=O)OC2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 5/20 0.36
EPHX1 P07099 2/20 0.36
ACHE P22303 6/20 0.36
GAA P10253 1/20 0.34
NAAA Q02083 3/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17883538 0.91 EPHX1 (0.45) EPHX2EPHX1ACHEGAANAAA
Octane SCHEMBL31147002 0.90 EPHX2 (0.39) EPHX2EPHX1ACHENAAA
SCHEMBL12047216 0.90 EPHX2 (0.39) EPHX2EPHX1ACHENAAA
SCHEMBL185586 0.90 EPHX2 (0.39) EPHX2EPHX1ACHENAAA
SCHEMBL22699687 0.90 EPHX2 (0.39) EPHX2EPHX1ACHENAAA
SCHEMBL19422674 0.90 ACHE (0.47) EPHX2EPHX1ACHEGAA
SCHEMBL13129125 0.88 NAAA (0.40) EPHX2EPHX1GAANAAATSHR
SCHEMBL14706863 0.86 TSHR (0.45) EPHX2GAANAAATSHR
SCHEMBL15850409 0.86 TSHR (0.45) EPHX2GAANAAATSHR
SCHEMBL12926806 0.85 EPHX2 (0.36) EPHX2EPHX1ACHEGAANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5578731-A ASYMMETRICAL HYDRAZINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1996-11-26 US disclosed
US-5554754-A PHOTOSTABILIZERS CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
US-5470980-A Light stabilizers for polymers that can be grafted to polymers CIBA-GEIGY CORPORATION (US) 1995-11-28 US disclosed
EP-0647626-A1 Azadicarboxylic acid derivatives containing hindered amine moieties as polymer stabilisers CIBA-GEIGY AG (CH) 1995-04-12 EP disclosed
US-5380828-A Stabilization by being grafted onto a polymer CIBA-GEIGY CORPORATION (US) 1995-01-10 US disclosed