Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585705 | 0.98 | PRMT1 (0.55) | PRMT1ADRA1AMAPK1LMNATSHR | |
| SCHEMBL17234580 | 0.92 | PRMT1 (0.47) | PRMT1ADRA1AMAPK1LMNATSHR | |
| SCHEMBL466337 | 0.92 | PRMT1 (0.47) | PRMT1ADRA1AMAPK1LMNATSHR | |
| SCHEMBL10752337 | 0.84 | ECE1 (0.43) | PRMT1ADRA1ALMNAPLA2G2AALDH1A1 | |
| SCHEMBL17234155 | 0.84 | ECE1 (0.43) | PRMT1ADRA1ALMNAPLA2G2AALDH1A1 | |
| SCHEMBL9307514 | 0.79 | PRMT1 (0.68) | PRMT1ADRA1AMAPK1LMNATSHR | |
| SCHEMBL2028710 | 0.79 | PRMT1 (0.68) | PRMT1ADRA1AMAPK1LMNATSHR | |
| SCHEMBL11039434 | 0.79 | PRMT1 (0.68) | PRMT1ADRA1AMAPK1LMNATSHR | |
| SCHEMBL7355410 | 0.78 | PRMT1 (0.50) | PRMT1ADRA1AMAPK1LMNATSHR | |
| SCHEMBL2172441 | 0.77 | PRMT1 (0.64) | PRMT1ADRA1AMAPK1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508383-A | Cyclic peptide LHRH antagonists | TAP HOLDINGS INC. (US) | 1996-04-16 | — | — | US | disclosed |