SCHEMBL466337

SCHEMBL466337

NN=C(N)NCCCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.47
ATM Q13315 1/20 0.44
ADRA1A P35348 1/20 0.44
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
PLA2G4A P47712 1/20 0.41
LMNA P02545 4/20 0.40
SLC22A6 Q4U2R8 1/20 0.40
EPHX2 P34913 1/20 0.40
FABP4 P15090 1/20 0.40
TSHR P16473 2/20 0.39
GABRR3 A8MPY1 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
HDAC3 O15379 1/20 0.39
GABBR2 O75899 1/20 0.39
CYP1A2 P05177 1/20 0.39
THRB P10828 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17234580 1.00 PRMT1 (0.47) PRMT1ATMADRA1ACA1CA2
SCHEMBL585705 0.94 PRMT1 (0.55) PRMT1ADRA1ALMNAEPHX2TSHR
SCHEMBL8944734 0.92 PRMT1 (0.59) PRMT1ADRA1APLA2G4ALMNAEPHX2
SCHEMBL17234155 0.87 ECE1 (0.43) PRMT1ADRA1ACA1CA2LMNA
SCHEMBL10752337 0.87 ECE1 (0.43) PRMT1ADRA1ACA1CA2LMNA
SCHEMBL28236290 0.83 PRMT1 (0.47) PRMT1ATMADRA1ACA1CA2
SCHEMBL19933297 0.82 ADRA1A (0.47) PRMT1ATMADRA1ACA1CA2
SCHEMBL25366603 0.80 PRMT1 (0.44) PRMT1ATMADRA1ACA1CA2
SCHEMBL2035521 0.78 PRMT1 (0.54) PRMT1ATMADRA1ACA1CA2
SCHEMBL33717 0.74 PRMT1 (0.50) PRMT1ATMADRA1APLA2G4ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1012247-A1 SHORT PEPTIDES WHICH SELECTIVELY MODULATE INTRACELLULAR SIGNALLING The Children's Medical Center Corporation (US) 2000-06-28 EP claimed
WO-1998053051-A1 SHORT PEPTIDES WHICH SELECTIVELY MODULATE INTRACELLULAR SIGNALLING THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1998-11-26 WO claimed
US-12378301-B2 B1SP fusion protein therapeutics, methods, and uses THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2025-08-05 US disclosed
CN-112533938-B Polypeptides self-assembled into nanoparticles 苏黎世联邦理工学院 2025-04-25 CN disclosed
CN-119546765-A Hybrid oligonucleotides 恩特拉达治疗学股份有限公司 2025-02-28 CN disclosed
CN-119390777-A Zwitterionic fluorescent probe containing dimeric targeting ligand and preparation method and application thereof 北京声光纳医疗科技有限公司 2025-02-07 CN disclosed
CN-119156395-A Cyclic peptides for delivery of therapeutic agents 恩特拉达治疗学股份有限公司 2024-12-17 CN disclosed
CN-118284434-A Compositions and methods for skipping exon 45 in duchenne muscular dystrophy 恩特拉达治疗学股份有限公司 2024-07-02 CN disclosed
CN-118215504-A Compounds and methods for skipping exon 44 in duchenne muscular dystrophy 恩特拉达治疗学股份有限公司 2024-06-18 CN disclosed
CN-117957022-A Antisense compounds and methods for targeting CUG repeats 安卓达治疗股份有限公司 2024-04-30 CN disclosed
CN-117915957-A Compositions and methods for modulating mRNA splicing 恩特拉达治疗学股份有限公司 2024-04-19 CN disclosed
US-20080182258-A1 Q3 SPARC DELETION MUTANT AND USES THEREOF ABRAXIS BIOSCIENCE, INC. (US) 2008-07-31 US disclosed
US-7332568-B2 Q3 SPARC deletion mutant and uses thereof ABRAXIS BIOSCIENCE, INC. (US) 2008-02-19 US disclosed
US-20080038280-A1 A32 Monoclonal Antibody Fusion Proteins For Use As Hiv Inhibitors And Vaccines GOVERNMENT OF THE UNITED STATES OF AMERICA (US) 2008-02-14 US disclosed
WO-2008017734-A1 POLYMYXIN DERIVATIVES AND USES THEREOF NORTHERN ANTIBIOTICS OY (FI) 2008-02-14 WO disclosed
WO-2008000079-A1 SECRETED PROTEIN ACIDIC AND RICH IN CYSTEINE (SPARC) AS CHEMOTHERAPEUTIC SENSITIZERS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2008-01-03 WO disclosed
EP-1869077-A2 Q3 SPARC DELETION MUTANT AND USES THEREOF Abraxis BioScience, Inc. (US) 2007-12-26 EP disclosed
US-20070212363-A1 Immunoglobulins with Potent and Broad Antiviral Activity THE GOV OF USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2007-09-13 US disclosed
WO-2006112930-A2 Q3 SPARC DELETION MUTANT AND USES THEREOF ABRAXIS BIOSCIENCE, INC. (US) 2006-10-26 WO disclosed
US-20060199248-A1 Q3 SPARC deletion mutant and uses thereof AMERICAN BIOSCIENCE, INC. (US) 2006-09-07 US disclosed