Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431673 | 1.00 | PRMT1 (0.50) | PRMT1ADRA1APLA2G2AMAPK1PLA2G4A | |
| SCHEMBL17234482 | 0.86 | LMNA (0.38) | PRMT1PLA2G2ALMNAKDM4EALDH1A1 | |
| SCHEMBL22578660 | 0.78 | F2 (0.36) | LMNAF2 | |
| SCHEMBL8944734 | 0.78 | PRMT1 (0.59) | PRMT1ADRA1APLA2G2AMAPK1PLA2G4A | |
| SCHEMBL585705 | 0.75 | PRMT1 (0.55) | PRMT1ADRA1APLA2G2AMAPK1LMNA | |
| SCHEMBL22765153 | 0.73 | NOS1 (0.36) | LMNACYP2C9CYP2C19ALDH1A1F2 | |
| Phosphoric Acid SCHEMBL7161899 | 0.73 | EPHX1 (0.42) | EPHX1F2 | |
| SCHEMBL9307514 | 0.73 | PRMT1 (0.68) | PRMT1ADRA1APLA2G2AMAPK1PLA2G4A | |
| SCHEMBL2028710 | 0.73 | PRMT1 (0.68) | PRMT1ADRA1APLA2G2AMAPK1PLA2G4A | |
| SCHEMBL11039434 | 0.73 | PRMT1 (0.68) | PRMT1ADRA1APLA2G2AMAPK1PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258398-A | Anticoagulants; platelet aggregation inhibitors | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1993-11-02 | — | — | US | disclosed |
| WO-1993011759-A1 | ANTITHROMBOTIC DIAMINOALKANOIC ACID DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1993-06-24 | — | — | WO | disclosed |