Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944723 | 0.85 | TSHR (0.39) | ALDH1A1ESR1HSD17B10TSHRKMT2A | |
| SCHEMBL8944710 | 0.79 | ALDH1A1 (0.35) | ALDH1A1ESR1HSD17B10TSHRKMT2A | |
| SCHEMBL8944528 | 0.78 | TSHR (0.37) | ALDH1A1ESR1HSD17B10TSHRKMT2A | |
| SCHEMBL8944706 | 0.76 | ALDH1A1 (0.39) | ALDH1A1ESR1HSD17B10TSHRKMT2A | |
| SCHEMBL13487849 | 0.74 | TSHR (0.42) | ALDH1A1ESR1HSD17B10TSHRKMT2A | |
| SCHEMBL8944553 | 0.73 | EPHX1 (0.34) | ALDH1A1ESR1HSD17B10TSHRKMT2A | |
| SCHEMBL7476147 | 0.73 | TSHR (0.39) | ALDH1A1ESR1HSD17B10TSHRKMT2A | |
| SCHEMBL17281376 | 0.73 | TSHR (0.39) | ALDH1A1ESR1HSD17B10TSHRKMT2A | |
| SCHEMBL8944945 | 0.71 | GAA (0.39) | ALDH1A1GAA | |
| SCHEMBL24914859 | 0.70 | ALDH1A1 (0.36) | ALDH1A1ESR1HSD17B10TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578731-A | ASYMMETRICAL HYDRAZINE DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| US-5554754-A | PHOTOSTABILIZERS | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5470980-A | Light stabilizers for polymers that can be grafted to polymers | CIBA-GEIGY CORPORATION (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0647626-A1 | Azadicarboxylic acid derivatives containing hindered amine moieties as polymer stabilisers | CIBA-GEIGY AG (CH) | 1995-04-12 | — | — | EP | disclosed |