Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22368526 | 0.81 | GAA (0.39) | GAAPOLBALDH1A1MAPT | |
| SCHEMBL8944723 | 0.81 | TSHR (0.39) | GAAHTTALDH1A1 | |
| SCHEMBL8944528 | 0.74 | TSHR (0.37) | GAAHTTALDH1A1 | |
| SCHEMBL8553282 | 0.73 | POLB (0.51) | GAAPOLBATMHTTALDH1A1 | |
| SCHEMBL11182545 | 0.73 | KCNA3 (0.38) | GAAPOLBALDH1A1LMNA | |
| SCHEMBL8944553 | 0.72 | EPHX1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8944710 | 0.72 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL8944778 | 0.71 | ALDH1A1 (0.35) | GAAALDH1A1 | |
| SCHEMBL19518768 | 0.71 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL13487849 | 0.70 | TSHR (0.42) | GAAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578731-A | ASYMMETRICAL HYDRAZINE DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| US-5554754-A | PHOTOSTABILIZERS | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5470980-A | Light stabilizers for polymers that can be grafted to polymers | CIBA-GEIGY CORPORATION (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0647626-A1 | Azadicarboxylic acid derivatives containing hindered amine moieties as polymer stabilisers | CIBA-GEIGY AG (CH) | 1995-04-12 | — | — | EP | disclosed |