Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837648 | 0.87 | MEN1 (0.45) | SMN1; SMN2TDP1L3MBTL1MAPTRAB9A | |
| SCHEMBL8887803 | 0.86 | ALDH1A1 (0.48) | SMN1; SMN2TDP1MAPTRAB9ACYP1A2 | |
| SCHEMBL4889359 | 0.84 | MMP2 (0.51) | SMN1; SMN2TDP1L3MBTL1MAPTRAB9A | |
| SCHEMBL30881314 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2TDP1L3MBTL1MAPTRAB9A | |
| SCHEMBL5545146 | 0.83 | POLB (0.42) | SMN1; SMN2TDP1L3MBTL1MAPTRAB9A | |
| SCHEMBL6578349 | 0.82 | TDP1 (0.46) | SMN1; SMN2TDP1L3MBTL1MAPTRAB9A | |
| SCHEMBL8531541 | 0.81 | POLB (0.56) | SMN1; SMN2MAPTRAB9AHDAC8HDAC3 | |
| SCHEMBL7104225 | 0.79 | POLB (0.46) | SMN1; SMN2TDP1L3MBTL1MAPTRAB9A | |
| SCHEMBL9226627 | 0.79 | MEN1 (0.46) | SMN1; SMN2MAPTRAB9ACYP1A2CYP2C19 | |
| SCHEMBL9349967 | 0.78 | TDP1 (0.55) | SMN1; SMN2TDP1L3MBTL1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519142-A | Homobidental, trifunctional linkers, method for their preparation and use in immunologically active conjugates | BOEHRINGER MANNHEIM GMBH (DE) | 1996-05-21 | — | — | US | disclosed |