SCHEMBL8944846

SCHEMBL8944846

C=CCCCOc1ccc(-c2ccc(-c3ccc(C4CCC(C)OC4)cc3F)cc2)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 2/20 0.31
FASN P49327 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944940 0.96 FPR2 (0.31) FPR2FASN
SCHEMBL8944833 0.91 HTR2C (0.36) FPR2FASN
SCHEMBL8944885 0.88 FPR2 (0.31) FPR2
SCHEMBL8948279 0.87 FPR2 (0.31) FPR2
SCHEMBL13000209 0.85 FPR2 (0.33) FPR2FASN
SCHEMBL13000178 0.85 FASN (0.30) FASN
SCHEMBL8944693 0.85 CNR2 (0.32) FPR2
SCHEMBL12999611 0.84 ALOX5AP (0.31) FASN
SCHEMBL8944039 0.84 CNR2 (0.36) FPR2
SCHEMBL8944866 0.84 FPR2 (0.33) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed