SCHEMBL8945111

SCHEMBL8945111

C[N+](C)(C)CCCCCCOC(=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
APEX1 P27695 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
LMNA P02545 4/20 0.46
NFKB1 P19838 3/20 0.46
KDM4E B2RXH2 2/20 0.46
ACHE P22303 2/20 0.46
PMP22 Q01453 2/20 0.46
TSHR P16473 2/20 0.46
RAB9A P51151 2/20 0.46
HSD17B10 Q99714 1/20 0.46
HRH3 Q9Y5N1 1/20 0.46
NPSR1 Q6W5P4 2/20 0.44
CHRM5 P08912 4/20 0.44
CHRM1 P11229 4/20 0.44
CHRM3 P20309 4/20 0.44
CHRM2 P08172 3/20 0.44
CHRM4 P08173 3/20 0.44
CHRNB2 P17787 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945372 0.91 CHRM5 (0.47) MEN1KMT2AAPEX1SMN1; SMN2LMNA
SCHEMBL31164016 0.85 RAD52 (0.54) LMNAACHETSHRNPSR1ADRA1A
SCHEMBL31164010 0.84 ALDH1A1 (0.47) SMN1; SMN2NFKB1ACHETSHRNPSR1
SCHEMBL31164013 0.82 DNM1 (0.50) LMNAACHENPSR1ADRA1ARAD52
SCHEMBL338845 0.82 CHRM1 (0.62) APEX1SMN1; SMN2LMNANFKB1ACHE
SCHEMBL31164022 0.80 RAD52 (0.58) ACHETSHRNPSR1RAD52
Choline SCHEMBL9298326 0.80 RAD52 (0.49) LMNAACHENPSR1ADRA1ARAD52
Iodide SCHEMBL10338189 0.79 SMN1; SMN2 (0.65) MEN1KMT2AAPEX1SMN1; SMN2LMNA
Tetramethylammonium Ion SCHEMBL31164008 0.79 EPHX1 (0.57) LMNAACHETSHRNPSR1RAD52
SCHEMBL5995962 0.79 DNM1 (0.56) LMNAACHENPSR1ADRA1ARAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489663-A TRIMERIZING ALIPHATIC AND/OR CYCLOALIPHATIC DIISOCYANATES USING TETRAALKYLAMMONIUM ALKYL CARBONATE OR MIXTURES WITH QUATERNARY AMMONIOALKYL CARBONATE CATALYSTS, DEACTIVATING CATALYST BASF AKTIENGESELLSCHAFT (DE) 1996-02-06 US disclosed