Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945508 | 0.87 | SKP2 (0.41) | ESR2SKP2CYP3A4ALDH1A1GAA | |
| SCHEMBL8945135 | 0.86 | SKP2 (0.42) | ESR2SKP2CYP3A4SLC5A1SLC5A2 | |
| SCHEMBL8945422 | 0.84 | ESR2 (0.42) | ESR2CYP3A4SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL8945523 | 0.83 | CYP2C9 (0.49) | ESR2SKP2CYP3A4SLC5A1SLC5A2 | |
| SCHEMBL8945167 | 0.83 | ESR2 (0.41) | ESR2CYP3A4SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL8945496 | 0.81 | SKP2 (0.48) | ESR2SKP2ALDH1A1SPHK1MAPT | |
| SCHEMBL7751598 | 0.81 | ESR2 (0.52) | ESR2CYP3A4SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL8945000 | 0.81 | SPHK1 (0.41) | ESR2CYP3A4SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL8945346 | 0.80 | SKP2 (0.47) | SKP2ALDH1A1SPHK1MAPTMEN1 | |
| SCHEMBL15043592 | 0.80 | ESR2 (0.47) | ESR2CYP3A4SLC5A1SLC5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |