SCHEMBL8945508

SCHEMBL8945508

Cc1cc(Cc2ccc(C3CCCCC3)cc2)ccc1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.41
NOS3 P29474 2/20 0.40
NOS1 P29475 2/20 0.40
NOS2 P35228 2/20 0.40
S1PR1 P21453 3/20 0.38
S1PR5 Q9H228 3/20 0.38
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 1/20 0.38
NFKB1 P19838 1/20 0.38
HTT P42858 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
S1PR3 Q99500 2/20 0.37
CARM1 Q86X55 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945151 0.87 ESR2 (0.44) SKP2ALDH1A1KDM4EMEN1GAA
SCHEMBL8945135 0.84 SKP2 (0.42) SKP2ALDH1A1KDM4EMEN1GAA
SCHEMBL8945400 0.82 NOS3 (0.41) NOS3NOS1NOS2ALDH1A1KDM4E
SCHEMBL790114 0.82 BACE1 (0.47) NOS3NOS1NOS2ALDH1A1TDP1
SCHEMBL8945523 0.82 CYP2C9 (0.49) SKP2ALDH1A1MEN1MAPTKMT2A
SCHEMBL8945136 0.82 KDM4E (0.38) NOS3NOS1NOS2ALDH1A1KDM4E
SCHEMBL8945176 0.80 EPHX2 (0.43) NOS3NOS1NOS2ALDH1A1KDM4E
SCHEMBL22298075 0.80 CYP3A4 (0.45) SKP2ALDH1A1TDP1BACE1CYP3A4
SCHEMBL25630463 0.80 ALDH1A1 (0.45) NOS3NOS1NOS2ALDH1A1TDP1
SCHEMBL8945496 0.80 SKP2 (0.48) SKP2ALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed