Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945015 | 0.92 | OPRL1 (0.39) | OPRL1CYP2C9ALDH1A1CYP3A4TSHR | |
| SCHEMBL8945131 | 0.91 | OPRL1 (0.38) | OPRL1CYP2C9ALDH1A1CYP3A4TSHR | |
| SCHEMBL8945369 | 0.90 | OPRL1 (0.37) | OPRL1CYP2C9ALDH1A1CYP3A4TSHR | |
| SCHEMBL8945231 | 0.90 | OPRL1 (0.37) | OPRL1CYP2C9ALDH1A1CYP3A4TSHR | |
| SCHEMBL8945279 | 0.90 | OPRL1 (0.37) | OPRL1CYP2C9ALDH1A1CYP3A4TSHR | |
| SCHEMBL8945411 | 0.89 | ALDH1A1 (0.39) | OPRL1ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL30767895 | 0.86 | OPRL1 (0.45) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL7732440 | 0.85 | CYP2C9 (0.36) | OPRL1CYP2C9ALDH1A1CYP3A4TSHR | |
| SCHEMBL6363303 | 0.85 | CYP2C9 (0.36) | OPRL1CYP2C9ALDH1A1CYP3A4TSHR | |
| SCHEMBL8945212 | 0.83 | ALDH1A1 (0.41) | OPRL1ALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |