Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945209 | 0.84 | HTR2C (0.36) | HTR2CHTR6HDAC4HTR2AHTR2B | |
| SCHEMBL8945420 | 0.84 | HTR2C (0.41) | HTR2CHTR6HDAC4HTR2AHTR2B | |
| SCHEMBL8945160 | 0.84 | HTR6 (0.36) | HTR6HDAC4GSK3BMAOAMAOB | |
| SCHEMBL8945208 | 0.83 | HTR2C (0.40) | HTR2CHTR6HDAC4HTR2AHTR2B | |
| SCHEMBL8945021 | 0.81 | HTR2C (0.38) | HTR2CHTR6HDAC4HTR2AHTR2B | |
| SCHEMBL8945139 | 0.80 | HTR2C (0.38) | HTR2CHTR6HDAC4OPRL1 | |
| SCHEMBL8945288 | 0.79 | HTR2C (0.37) | HTR2CHTR6HTR2AOPRL1 | |
| SCHEMBL8945379 | 0.79 | HTR2C (0.37) | HTR2CHTR6HTR2AOPRL1 | |
| SCHEMBL8945242 | 0.79 | HTR2C (0.37) | HTR2CHTR6HTR2AOPRL1 | |
| SCHEMBL8945265 | 0.76 | HTR6 (0.36) | HTR2CHTR6HTR2AHTR2BGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |