Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SCN4A | P35499 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8945292 | 0.99 | FAAH (0.44) | FAAHKMT2AMEN1SCN4AALDH1A1 | |
| SCHEMBL8945444 | 0.89 | FAAH (0.47) | FAAHKMT2AMEN1SCN4AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8945073 | 0.88 | FAAH (0.47) | FAAHKMT2AMEN1SCN4AALDH1A1 | |
| SCHEMBL8945277 | 0.88 | KMT2A (0.40) | FAAHKMT2AMEN1SCN4AKCNH2 | |
| SCHEMBL8944957 | 0.87 | FAAH (0.41) | FAAHKMT2AMEN1SCN4AALDH1A1 | |
| SCHEMBL8945002 | 0.83 | FAAH (0.42) | FAAHKMT2ASCN4AALDH1A1KCNH2 | |
| Hydrochloric Acid SCHEMBL8945257 | 0.83 | FAAH (0.41) | FAAHKMT2ASCN4AALDH1A1KCNH2 | |
| SCHEMBL8945252 | 0.82 | SCN4A (0.51) | FAAHSCN4AKCNH2SCN5A | |
| SCHEMBL8944917 | 0.78 | FAAH (0.44) | FAAHKMT2AMEN1SCN4AALDH1A1 | |
| SCHEMBL8945192 | 0.77 | FAAH (0.40) | FAAHSCN4AKCNH2SCN5AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |