Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 10/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944917 | 0.88 | FAAH (0.44) | SCN4AKCNH2SCN5AFAAHTACR1 | |
| SCHEMBL8945002 | 0.87 | FAAH (0.42) | SCN4AKCNH2SCN5AFAAHTACR1 | |
| SCHEMBL8945192 | 0.87 | FAAH (0.40) | SCN4AKCNH2SCN5AFAAH | |
| SCHEMBL8945013 | 0.87 | FAAH (0.44) | SCN4AKCNH2SCN5AFAAH | |
| Hydrochloric Acid SCHEMBL8945185 | 0.87 | FAAH (0.44) | SCN4AKCNH2SCN5AFAAHTACR1 | |
| SCHEMBL8944957 | 0.86 | FAAH (0.41) | SCN4AKCNH2SCN5AFAAH | |
| Hydrochloric Acid SCHEMBL8945257 | 0.86 | FAAH (0.41) | SCN4AKCNH2SCN5AFAAHTACR1 | |
| SCHEMBL8945141 | 0.85 | FAAH (0.47) | SCN4AKCNH2SCN5AFAAHKAT6A | |
| SCHEMBL8945137 | 0.84 | SCN4A (0.50) | SCN4AKCNH2SCN5AFAAHTACR1 | |
| SCHEMBL8945316 | 0.83 | SCN4A (0.53) | SCN4AKCNH2SCN5AFAAHTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |