Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 7/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945264 | 0.85 | FAAH (0.48) | SCN4AFAAHAKT1ROCK1PRKACA | |
| SCHEMBL8945252 | 0.83 | SCN4A (0.51) | SCN4AFAAHKCNH2SCN5AACHE | |
| SCHEMBL8945047 | 0.83 | FAAH (0.46) | SCN4AFAAHKCNH2SCN5A | |
| SCHEMBL8945126 | 0.83 | FAAH (0.48) | SCN4AFAAHKCNH2SCN5A | |
| SCHEMBL8945327 | 0.83 | FAAH (0.45) | SCN4AFAAHKCNH2SCN5A | |
| SCHEMBL8945123 | 0.83 | FAAH (0.48) | SCN4AFAAHKCNH2SCN5A | |
| SCHEMBL8945066 | 0.83 | FAAH (0.48) | SCN4AFAAHKCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL8945297 | 0.81 | FAAH (0.47) | SCN4AFAAHKCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL8945091 | 0.81 | FAAH (0.47) | SCN4AFAAHKCNH2SCN5A | |
| SCHEMBL8945005 | 0.81 | FAAH (0.46) | SCN4AFAAHKCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |