Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945348 | 1.00 | SPHK1 (0.41) | SPHK1CYP2C9SPHK2GRM2CYP3A4 | |
| SCHEMBL8945340 | 1.00 | SPHK1 (0.41) | SPHK1CYP2C9SPHK2GRM2CYP3A4 | |
| SCHEMBL8945152 | 0.99 | SPHK1 (0.40) | SPHK1CYP2C9SPHK2GRM2CYP3A4 | |
| SCHEMBL8945040 | 0.95 | SPHK1 (0.38) | SPHK1CYP2C9SPHK2ALDH1A1LMNA | |
| SCHEMBL8945075 | 0.91 | CYP2C9 (0.44) | SPHK1CYP2C9CYP3A4ALDH1A1LMNA | |
| SCHEMBL8945230 | 0.86 | ALDH1A1 (0.33) | SPHK1CYP2C9CYP3A4ALDH1A1LMNA | |
| SCHEMBL7752525 | 0.85 | SPHK1 (0.52) | SPHK1CYP2C9SPHK2ALDH1A1LMNA | |
| SCHEMBL7928056 | 0.85 | SPHK1 (0.52) | SPHK1CYP2C9SPHK2ALDH1A1LMNA | |
| SCHEMBL7752570 | 0.85 | SPHK1 (0.52) | SPHK1CYP2C9SPHK2ALDH1A1LMNA | |
| SCHEMBL8164282 | 0.84 | SPHK1 (0.50) | SPHK1CYP2C9SPHK2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |