SCHEMBL8945075

SCHEMBL8945075

CCCC1CCC(c2ccc(Cc3ccc(N)cc3)c(C)c2)CC1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.44
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
SPHK1 Q9NYA1 3/20 0.34
ESR2 Q92731 2/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945040 0.93 SPHK1 (0.38) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945152 0.92 SPHK1 (0.40) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945253 0.91 SPHK1 (0.41) CYP2C9ALDH1A1LMNAMAPTSPHK1
SCHEMBL8945348 0.91 SPHK1 (0.41) CYP2C9ALDH1A1LMNAMAPTSPHK1
SCHEMBL8945340 0.91 SPHK1 (0.41) CYP2C9ALDH1A1LMNAMAPTSPHK1
SCHEMBL8945230 0.90 ALDH1A1 (0.33) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945090 0.88 CYP2C9 (0.47) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945310 0.86 CYP2C9 (0.43) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945434 0.86 CYP2C9 (0.43) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945272 0.84 ESR2 (0.38) ALDH1A1SPHK1ESR2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed