SCHEMBL8945368

SCHEMBL8945368

Cc1ccc(S(=O)(=O)SCCCc2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
G6PD P11413 2/20 0.70
BCHE P06276 9/20 0.67
ACHE P22303 9/20 0.67
CNR2 P34972 3/20 0.50
ALDH1A1 P00352 1/20 0.47
CA2 P00918 1/20 0.46
CA12 O43570 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
ATM Q13315 1/20 0.46
CA9 Q16790 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
MCHR1 Q99705 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6954708 0.95 G6PD (0.68) G6PDBCHEACHECNR2ALDH1A1
SCHEMBL11790970 0.92 BCHE (0.73) G6PDBCHEACHECNR2ALDH1A1
SCHEMBL11705721 0.89 CA2 (0.53) G6PDBCHEACHEALDH1A1CA2
SCHEMBL20595267 0.83 G6PD (0.92) G6PDBCHEACHEALDH1A1CA2
SCHEMBL14024173 0.83 G6PD (1.00) G6PDBCHEACHEALDH1A1CA2
SCHEMBL11025388 0.81 G6PD (0.89) G6PDBCHEACHEALDH1A1CA2
SCHEMBL13344367 0.81 G6PD (0.89) G6PDBCHEACHEALDH1A1CA2
SCHEMBL11607679 0.80 BCHE (1.00) G6PDBCHEACHEALDH1A1CA12
SCHEMBL17378580 0.79 G6PD (0.57) G6PDBCHEACHEALDH1A1CA12
SCHEMBL6649884 0.79 G6PD (0.84) G6PDBCHEACHEALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510375-A VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS WARNER-LAMBERT COMPANY (US) 1996-04-23 US disclosed