Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945541 | 0.93 | NQO1 (0.40) | NQO1ALDH1A1LMNAMEN1ABCB11 | |
| SCHEMBL8945669 | 0.86 | ALDH1A1 (0.55) | NQO1ALDH1A1LMNAMEN1ABCB11 | |
| SCHEMBL8945409 | 0.82 | NQO1 (0.40) | NQO1ALDH1A1LMNAMEN1ABCB11 | |
| SCHEMBL8945424 | 0.81 | LMNA (0.50) | NQO1ALDH1A1LMNAMEN1CYP1A2 | |
| SCHEMBL8945416 | 0.81 | NQO1 (0.47) | NQO1ALDH1A1LMNAMEN1TSHR | |
| SCHEMBL8945584 | 0.77 | NQO1 (0.38) | NQO1ALDH1A1LMNAMEN1ABCB11 | |
| SCHEMBL8945602 | 0.76 | AKR1C3 (0.54) | NQO1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8945588 | 0.76 | KDM4E (0.49) | NQO1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8945414 | 0.75 | NQO1 (0.53) | NQO1ALDH1A1LMNAMEN1ABCB11 | |
| SCHEMBL8945418 | 0.71 | NQO1 (0.62) | NQO1ALDH1A1LMNAMEN1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510375-A | VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |