Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | IL2 | P60568 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945456 | 0.89 | RARB (0.36) | RARBRARARARGALOX5APFEN1 | |
| SCHEMBL8945787 | 0.85 | RARB (0.39) | RARBRARARARGLTA4HGCGR | |
| SCHEMBL8945026 | 0.83 | RAB9A (0.44) | RARBRARARARGALOX5APFEN1 | |
| SCHEMBL8946222 | 0.82 | RARB (0.40) | RARBRARARARGLTA4HLMNA | |
| SCHEMBL12999938 | 0.81 | FEN1 (0.37) | ALOX5APFEN1IL2LMNAHTR2C | |
| SCHEMBL8943511 | 0.80 | TSHR (0.33) | IL2LMNAHTR2CHTR2AALDH1A1 | |
| SCHEMBL8942564 | 0.76 | RAB9A (0.49) | RARBLTA4HMEN1ALDH1A1KMT2A | |
| SCHEMBL2855559 | 0.76 | RARB (0.52) | RARBRARARARGLMNAS1PR1 | |
| SCHEMBL16856094 | 0.76 | CNR2 (0.46) | RARBRARAS1PR1HTR2CHTR2B | |
| SCHEMBL10462030 | 0.76 | RARB (0.54) | RARBRARARARGS1PR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |