Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945412 | 0.82 | CYP2D6 (0.35) | CYP2D6CYP2C19ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8945485 | 0.74 | MAOB (0.37) | — | |
| SCHEMBL9642706 | 0.73 | — | — | |
| SCHEMBL8560163 | 0.72 | MEN1 (0.31) | — | |
| SCHEMBL8560488 | 0.72 | — | — | |
| SCHEMBL9642216 | 0.72 | SMN1; SMN2 (0.35) | LMNA | |
| SCHEMBL9641789 | 0.69 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL9641238 | 0.69 | — | — | |
| SCHEMBL8558320 | 0.69 | — | — | |
| SCHEMBL6992694 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494887-A | Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1996-02-27 | — | — | US | disclosed |