Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 3/20 | 0.42 |
| ▸ | NQO1 | P15559 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945626 | 0.87 | NQO1 (0.50) | VKORC1NQO1KDM4ELMNAMAPT | |
| SCHEMBL8945341 | 0.86 | NQO1 (0.40) | VKORC1NQO1LMNA | |
| SCHEMBL8945587 | 0.84 | L3MBTL1 (0.41) | VKORC1NQO1KDM4ELMNAMAPT | |
| SCHEMBL8945477 | 0.79 | VKORC1 (0.39) | VKORC1NQO1KDM4ELMNAMAPT | |
| SCHEMBL8945575 | 0.79 | NQO1 (0.40) | VKORC1NQO1 | |
| SCHEMBL8945632 | 0.77 | NQO1 (0.51) | VKORC1NQO1MAPT | |
| SCHEMBL8945550 | 0.73 | NQO1 (0.50) | VKORC1NQO1LMNA | |
| SCHEMBL8945281 | 0.72 | LMNA (0.47) | NQO1KDM4ELMNAMAPT | |
| SCHEMBL8945635 | 0.71 | NQO1 (0.41) | VKORC1NQO1KDM4E | |
| SCHEMBL8945414 | 0.71 | NQO1 (0.53) | VKORC1NQO1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510375-A | VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |